tight junction protein ZO-3; Zonula occludens protein 3; Zona occludens protein 3; tight junction protein 3 (TJP3, ZO3)

Function

• interacts with occludin, claudins & ZO-1
• interacts with INADL (putative)
• interacts with UBN1

Structure

• belongs to the MAGUK family
• contains 1 guanylate kinase-like domain
• contains 3 PDZ domain (DHR domain)s
• contains 1 SH3 domain

Compartment

• cell membrane; peripheral membrane protein, cytoplasmic side (putative)
• cell junction, tight junction

More general terms

• tight juntion protein or zona occludens protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=27134
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:27134
• UniProt: http://www.uniprot.org/uniprot/O95049.html