Pick-1 protein
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Function
- binds to AMPA receptor & protein kinase C
Structure
- PDZ domain of Pick-1 binds to the C terminus of the GluR2 & GluR3 subunits of the AMPA receptor
More general terms
References
- ↑ Sheng M. Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7058-61. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11416187
- ↑ Perez JL, Khatri L, Chang C, Srivastava S, Osten P, Ziff EB. PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. J Neurosci. 2001 Aug 1;21(15):5417-28. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11466413