synaptotagmin-13; synaptotagmin XIII; SytXIII (SYT13, KIAA1427)

Function

• role in transport vesicle docking to the plasma membrane
• interacts with NRXN1

Structure

• the first C2 domain/C2A does not mediate Ca+2-dependent phospholipid binding (putative)
• the 2nd C2 domain binds phospholipids (Ca+2-independent)
• belongs to the synaptotagmin family
• contains 2 C2 domains

Compartment

membrane

Expression

expressed in brain, pancreas & kidney

More general terms

• synaptotagmin
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57586
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57586
• OMIM: https://mirror.omim.org/entry/607716
• UniProt: http://www.uniprot.org/uniprot/Q7L8C5.html