follistatin-related protein 3 (follistatin-like 3, follistatin-related gene protein, FSTL3, FLRG, UNQ674/PRO1308)

Function

• binding protein for activin & BMP-2

Structure

• contains 2 follistatin-like domains
• contains 2 Kazal-like domains

Compartment

secreted, nucleus ?

Expression

expressed in a wide range of tissues

Pathology

• chromosomal translocation t(11;19)(q13;p13) involving FSTL3 with CCDN1 is found in a case of B-cell chronic lymphocytic leukemia

More general terms

• follistatin-related protein (follistatin-like protein)

Database

• OMIM: https://mirror.omim.org/entry/605343
• UniProt: http://www.uniprot.org/uniprot/O95633.html