VPS10 domain-containing receptor SorCS1 (SORCS1, SORCS)

Structure

• belongs to the VPS10-related sortilin family, SORCS subfamily
• contains 5 BNR repeats
• contains 1 PKD domain

Compartment

• membrane; single-pass type 1 membrane protein

Alternative splicing

named isoforms=4

Expression

• detected in fetal & infant brain & in fetal retina

More general terms

• VPS10 domain-containing receptor SorCS (SORCS)
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=114815
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:114815
• OMIM: https://mirror.omim.org/entry/606283
• UniProt: http://www.uniprot.org/uniprot/Q8WY21.html