protocadherin-24; cadherin-related family member 2; protocadherin LKC; PC-LKC (CDHR2, PCDH24, PCLKC)

Function

• contact inhibition at the lateral surface of epithelial cells
• interacts with MAST2

Compartment

• present at cell junctions & apical surface of epithelial cells
• colocalizes with actin at microvilli-like structures which protrude from apical surface

Expression

• expressed in liver, kidney, colon > small intestine

Pathology

• down-regulated in a number of liver cancers & colon cancers

More general terms

• protocadherin (PCDH)

Additional terms

• cadherin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54825
• UniProt: http://www.uniprot.org/uniprot/Q9BYE9.html