protocadherin-7; brain-heart protocadherin; BH-Pcdh (PCDH7, BHPCDH)

Function

• isoform C is phosphorylated on Ser-1130 upon DNA damage, probably by ATM or ATR

Structure

contains 7 cadherin domains

Compartment

• cell membrane
• single-pass type 1 membrane protein

Alternative splicing

named isoforms=3; A, B, C

Expression

• expressed predominantly in brain & heart
• lower levels of expression in other tissues

More general terms

• protocadherin (PCDH)
• phosphoprotein

Additional terms

• cadherin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5099
• OMIM: https://mirror.omim.org/entry/602988
• UniProt: http://www.uniprot.org/uniprot/O60245.html