Mas-related G protein-coupled receptor member X2 (MRGPRX2, MRGX2)

Function

• cortistatin-14 seems to be a high potency ligand
• nociceptor function &/or development
  • sensation or modulation of pain
• ortistatin-14 may be ligand
• Gq protein-coupled receptor (putative)

Structure

• belongs to the G-protein coupled receptor 1 family mas subfamily

Compartment

cell membrane

Expression

• limited expression profile
  • expressed in CNS & peripheral nervous system
  • highest in dorsal root ganglion

More general terms

• mas-related G protein coupled receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1171
• OMIM: https://mirror.omim.org/entry/607228
• UniProt: http://www.uniprot.org/uniprot/Q96LB1.html