cortistatin

Function

• binds to all human somatostatin receptor subtypes
• coricostatin-14 may be ligand for MRGPRX2 (Mas-related G-protein coupled receptor member X2)
• sleep regulation locomotor activity
• cortical function

Compartment

secreted

Expression

• expressed in a subset of GABAergic cells in cortex & hippocampus

More general terms

• secreted protein

Additional terms

• somatostatin receptor

Component of

• clioquinol/cortisol/cortistatin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1325
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1325
• OMIM: https://mirror.omim.org/entry/602784
• UniProt: http://www.uniprot.org/uniprot/O00230.html