corticotropin-releasing factor receptor 2; CRF-R 2; CRF2; corticotropin-releasing hormone receptor 2; CRH-R 2 (CRHR2 CRF2R CRH2R)

Function

• receptor for corticotropin releasing factor
• high-affinity CRF binding
• also binds to urocortin 1, 2 & 3
• activity is mediated by G proteins which activate adenylyl cyclase

Structure

belongs to the G-protein coupled receptor 2 family

Compartment

cell membrane

Alternative splicing

named isoforms=3; alpha, beta, gamma

More general terms

• corticotropin-releasing factor/hormone [CRF/CRH] receptor

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1395
• OMIM: https://mirror.omim.org/entry/602034
• UniProt: http://www.uniprot.org/uniprot/Q13324.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1395