muscarinic M3 receptor; muscarinic acetylcholine receptor M3 (CHRM3)

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Function

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

Expression

Pharmacology

More general terms

References

  1. 1.0 1.1 Conkilin et al PNAS 85:8698 (1988)
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1131
  3. Mukerji G et al, Localization of M2 and M3 muscarininc receptors in human bladder disorders and their clinical correlations. J Urol. 2006, 176:367 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16753445
  4. 4.0 4.1 Gromada J & Hughes TE Ringing the dinner bell for insulin: muscarinic M3 receptor activity in the control of pancreatic beta cell function. Cell Metab. 2006, 3:390 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16753574
  5. 5.0 5.1 Wang Z et al Functional M3 muscarinic acetylcholine receptors in mammalian hearts Br J Pharmacol 2004, 142:395 PMID: https://www.ncbi.nlm.nih.gov/pubmed/15148264
  6. 6.0 6.1 6.2 Ehlert FJ Pharmacologic analysis of the contractile role of M2 and M3 muscarinic receptors in smooth muscle. Receptors Channels 2003, 9:261 PMID: https://www.ncbi.nlm.nih.gov/pubmed/12893538
  7. Kruse AC et al Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature. 2012 Feb 22;482(7386):552-6. doi:http://dx.doi.org/ 10.1038/nature10867. PMID: https://www.ncbi.nlm.nih.gov/pubmed/22358844

Database