microfibrillar-associated protein 2; MFAP-2; microfibril-associated glycoprotein 1; MAGP; MAGP-1 (MFAP2, MAGP1)

Function

• component of the elastin-associated microfibrils
• forms intermolecular disulfide bonds either with other MAGP-1 molecules or with other components of the microfibrils
• may form transglutaminase cross-links
• forms a ternary complex with BGN & ELN (putative)

Structure

• O-glycosylated
• belongs to the MFAP family
• contains 1 SXC (ShKT) domain

Compartment

• secreted, extracellular space, extracellular matrix

Alternative splicing

named isoforms=3; A, A', B

More general terms

• microfibrillar associated protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4237
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4237
• OMIM: https://mirror.omim.org/entry/156790
• UniProt: http://www.uniprot.org/uniprot/P55001.html