oligodendrocyte-myelin glycoprotein (OMG OMGP)

Function

• cell adhesion molecule
• role in myelination in the central nervous system
• binds to RTN4R (putative)

Structure

• O-glycosylated in its Ser/Thr-rich repeat domain (putative)
• contains 8 LRR repeats (leucine-rich repeats)

Compartment

cell membrane; lipid-anchor, GPI-anchor

Expression

• oligodendrocytes & myelin of the central nervous system

Notes

• do not confuse with myelin-oligodendrocyte glycoprotein (MOG)

More general terms

• myelin protein
• glypiated protein
• leucine-rich repeat-containing protein (LRRC)

Database

• UniProt: http://www.uniprot.org/uniprot/P23515.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4974
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4974
• OMIM: https://mirror.omim.org/entry/164345