AP-3 complex subunit beta-2; adapter-related protein complex 3 subunit beta-2; adaptor protein complex AP-3 beta-2 subunit; AP-3 complex beta-2 subunit; beta3B-adaptin; clathrin assembly protein complex 3 beta-2 large chain; neuron-specific vesicle coat protein beta-NAP (AP3B2)

Function

• subunit of non-clathrin- & clathrin-associated adaptor protein complex 3 (AP-3)

Structure

• belongs to the adaptor complexes large subunit family

Compartment

• Golgi, cytoplasmic vesicle
• clathrin-coated vesicle membrane
• peripheral membrane, cytoplasmic sid
• component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (putative)

Expression

• expression is specific to nervous system
• expressed in nerve terminal & cell body, & is associated with nerve-terminal vesicles
• expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors & graded in cerebral cortex (deeper layers exhibit stronger expression)
• expressed from early in development through adulthood

More general terms

• beta adaptin (adaptor-related protein complex, beta subunit)
• phosphoprotein

Additional terms

• clathrin (triskelion)

Component of

• HA3/AP3 adaptor complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8120
• OMIM: https://mirror.omim.org/entry/602166
• UniProt: http://www.uniprot.org/uniprot/Q13367.html