voltage-gated K+ channel subunit beta-2; K+ channel subunit beta-2; Kv-beta-2; HKvbeta2 (KCNAB2, KCNA2B, KCNK2)

Function

• accessory K+ channel protein
• modulates activity of the pore-forming alpha subunit
• alters functional properties of Kv1.4
• forms heteromultimeric complex with alpha subunits
• forms a ternary complex with SQSTM1 & PRKCZ (putative)
• phosphorylated by PRKCZ; may be regulated by incorporation in a complex composed of PRKCZ & SQSTM1 (putative)

Structure

• alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit (probable)
• belongs to the shaker K+ channel beta subunit family

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

More general terms

• voltage-gated K+ channel beta subunit
• phosphoprotein

Additional terms

• voltage-gated K+ channel

Database

• UniProt: http://www.uniprot.org/uniprot/Q13303.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8514
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8514
• OMIM: https://mirror.omim.org/entry/601142