PDZ & LIM domain protein 4; LIM protein RIL; reversion-induced LIM protein (PDLIM4, RIL)

Function

• phosphorylated on Tyr
• can be dephosphorylated by PTPN13 (putative)
• interacts with the LIM domain with the 2nd & 4th PDZ domains of PTPN13 (putative)

Structure

• contains 1 LIM Zn+2-binding domain
• contains 1 PDZ domain (DHR domain)

Alternative splicing

named isoforms=2

Expression

• isoform 2 is found in brain

Polymorphism

• genetic variations in PDLIM4 may be correlated with bone mineral density

More general terms

• PDZ & LIM domain protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8572
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8572
• OMIM: https://mirror.omim.org/entry/603422
• UniProt: http://www.uniprot.org/uniprot/P50479.html