DPH3 homolog (CSL-type zinc finger-containing protein 2, DelGEF-interacting protein 1, DelGIP1, DPH3, DESR1, ZCSL2)

Function

• required in 1st step in the synthesis of diphthamide
• down-regulation increases extracellular release of proteoglycans
• stimulates binding of GNEFR to SEC5

Structure

• contains 1 DPH-type zinc finger

Alternative splicing

named isoforms=2

Expression

• widely expressed
• highest levels in small intestine, spleen, thymus, heart, liver, lung

More general terms

• zinc finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96FX2.html