secretion-regulating guanine nucleotide exchange factor (guanine nucleotide exchange factor-related protein, deafness locus-associated putative guanine nucleotide exchange factor, DelGEF, SERGEF, DELGEF, GNEFR)

Function

• probable guanine nucleotide exchange factor
• may be involved in secretion
• interaction with SEC5 (Mg+2 or Mn+2 dependent) stimulated by dCTP or GTP

Structure

• contains 7 RCC1 repeats

Compartment

cytoplasm, nucleus

Alternative splicing

named isoforms=2

More general terms

• guanine nucleotide exchange factor

Database

• OMIM: https://mirror.omim.org/entry/606051
• UniProt: http://www.uniprot.org/uniprot/Q9UGK8.html