CXXC-type zinc finger protein 6; leukemia-associated protein with a CXXC domain (CXXC6, TET1, KIAA1676, LCX)

Function

• fetal development of heart, lung & brain (putative)

Structure

• contains 1 CXXC-type zinc finger

Compartment

nucleus

Expression

• expressed in fetal heart, lung, brain, & in adult skeletal muscle, thymus, ovary
• not expressed in adult heart, lung or brain

Pathology

• chromosomal translocation t(10;11)(q22;q23) of CXXC6 with MLL (5' MLL-CXXC6 3') is associated with acute leukemia (rare)

More general terms

• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/607790
• UniProt: http://www.uniprot.org/uniprot/Q8NFU7.html