protein kinase C-binding protein 1; cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; zinc finger MYND domain-containing protein 8 (ZMYND8, KIAA1125, PRKCBP1, RACK7)

Function

• phosphorylated upon DNA damage, probably by ATM or ATR
• interacts in vitro with PRKCB1

Structure

• contains 1 bromo domain
• contains 1 MYND-type Zn+2 finger
• contains 1 PHD-type Zn+2 finger
• contains 1 PWWP domain

Alternative splicing

named isoforms=9

Expression

• expressed in all tissues examined
• highest expression in brain, lung, pancreas, & placenta

Pathology

• expressed in cutaneous T-cell lymphomas (CTCL)

More general terms

• zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23613
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23613
• UniProt: http://www.uniprot.org/uniprot/Q9ULU4.html