ADP-ribosylation factor 4 (ARF4, ARF2)

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Function

GTP-binding protein
activates ADP-ribosyltransferase (putative)
role in protein trafficking;
may modulate vesicle budding & uncoating within the Golgi

Structure

belongs to the small GTPase superfamily, Arf family

Compartment

Pathology

allosteric activator of the cholera toxin catalytic subunit

Notes

originally thought to be ARF2

More general terms

ADP-ribosylation factor [ARF] subfamily protein

References

↑ UniProt http://www.uniprot.org/uniprot/P18085.html
↑ Kahn RA, Der CJ, Bokoch GM. The ras superfamily of GTP-binding proteins: guidelines on nomenclature. FASEB J. 1992 May;6(8):2512-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1592203
↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=378

Database

UniProt: http://www.uniprot.org/uniprot/P18085.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=378
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:378
OMIM: https://mirror.omim.org/entry/601177

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