EP300-interacting inhibitor of differentiation 2B (EID-2B, EID-2-like inhibitor of differentiation 3, EID-3, EID2B, EID3)

Function

• acts as a repressor of MYOD-dependent transcription, glucocorticoid receptor-dependent transcription, & muscle differentiation
• interacts with HDAC1 & HDAC2

Structure

• homodimer & heterodimer with EID2
• C-terminal portion of EID2B is required for nuclear localization

Compartment

nucleus

More general terms

• EP300-interacting inhibitor of differentiation

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1262
• UniProt: http://www.uniprot.org/uniprot/Q96D98.html