XP E-correcting protein

^[1]^[2]

Function

binds specifically to UV-irradiated DNA^[1]
also recognizes DNA damage induced by nitrogen mustard, MNNG, 4NQO, 8-methoxypsoralen, cis & trans DDP & apurinic DNA^[2]
it is the only XP-correcting protein that is not absolutely required for DNA excision repair in vitro
may also serve another facilitatory role in nucleotide excision repair

↑ ^1.0 ^1.1 Lehmann AR. Nucleotide excision repair and the link with transcription. Trends Biochem Sci. 1995 Oct;20(10):402-5. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8533152
↑ ^2.0 ^2.1 Payne A, Chu G. Xeroderma pigmentosum group E binding factor recognizes a broad spectrum of DNA damage. Mutat Res. 1994 Oct 1;310(1):89-102. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7523888