doublecortin domain-containing protein 1; doublecortin domain-containing 5 protein (DCDC1, DCDC5, KIAA1493)

Function

• microtubule-binding protein
• role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis
• interacts with dynein intermediate chain, tubulin, RAB8A, RAB3IP, NUDC, PAFAH1B1 & DCTN1

Compartment

• midbody
• cytoplasm, cytoskeleton, spindle
• associated with stabilized microtubules of the mitotic spindle during metaphase & with midbody microtubules during cytokinesis

Alternative splicing

named isoforms=3

More general terms

• doublecortin domain-containing protein (DCDC)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=341019
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:341019
• OMIM: https://mirror.omim.org/entry/608062
• UniProt: http://www.uniprot.org/uniprot/M0R2J8.html