BAG family molecular chaperone regulator 3; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; Docking protein CAIR-1 (BAG3, BIS)
Jump to navigation
Jump to search
Function
- inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release
- has anti-apoptotic activity
- binds to the ATPase domain of HSP70/HSC chaperones
- binds to Bcl-2 & PLC-gamma
Structure
- contains 1 BAG domain
- contains 2 WW domains
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/O95817.html
- ↑ Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/genes/BAG3ID43160ch10q26.html
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9531
Database
- Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9531
- Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9531
- OMIM: https://mirror.omim.org/entry/603883
- UniProt: http://www.uniprot.org/uniprot/O95817.html
- Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9531