FYVE, RhoGEF & PH domain-containing protein 6 (zinc finger FYVE domain-containing protein 24, FGD6, KIAA1362, ZFYVE24)

Function

• may activate CDC42 by exchanging bound GDP for free GTP
• role in regulating the actin cytoskeleton & cell shape

Structure

• contains 1 DH domain (DBL-homology domain
• contains 1 FYVE-type zinc finger
• contains 2 PH domains

Compartment

cytoplasm

Alternative splicing

named isoforms=2

More general terms

• zinc finger FYVE domain-containing protein (ZFYVE)

Database

• UniProt: http://www.uniprot.org/uniprot/Q6ZV73.html