FYVE, RhoGEF & PH domain-containing protein 5 (zinc finger FYVE domain-containing protein 23, FGD5, ZFYVE23)

Function

• activates CDC42 via exchanging bound GDP for free GTP (putative)
• regulates actin cytoskeleton & cell shape (putative)

Structure

• contains 1 DBL-homology domain (DH domain)
• contains 1 FYVE-type zinc finger
• contains 2 PH domains

Compartment

cytoplasm

Alternative splicing

named isoforms=2

More general terms

• zinc finger FYVE domain-containing protein (ZFYVE)

Database

• UniProt: http://www.uniprot.org/uniprot/Q6ZNL6.html