pleiotropic regulator 1 (PLRG1)

Function

• necessary for spliceosome assembly & for pre-mRNA splicing
• binds CDC5L
• component of CDC5L multiprotein complex

Compartment

present in nuclear speckles

More general terms

• splicing factor; snRNP-associated protein
• WD repeat protein family

Database

• OMIM: https://mirror.omim.org/entry/605961
• UniProt: http://www.uniprot.org/uniprot/O43660.html