sperm-associated antigen 16 protein (Pf20 protein homolog, SPAG16, PF20)

Function

• role in sperm flagellar function
• interacts with SPAG6

Structure

contains 7 WD repeats

Compartment

• cytoplasm, cell projection, cilium, flagellum
• detected on the sperm flagellum
• detected in the central apparatus of the axoneme
• colocalizes with SPAG6 on microtubules

Alternative splicing

named isoforms=5

Expression

• isoform 1 is detected in testis
• isoform 4 is detected in testis & brain, & at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea, liver

More general terms

• WD repeat protein family

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N0X2.html