WD repeat & SOCS box-containing protein 2; WSB-2; CS box-containing WD protein (WSB2)

Function

• may be a substrate-recognition component of an elongin-Cullin-SOCS-box protein (ECS) E3 ligase complex which mediate ubiquitination & subsequent proteasomal degradation of target proteins (putative)
• protein modification; protein ubiquitination

Structure

• the SOCS box domain mediates the interaction with the elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes (putative)
• contains 1 SOCS box domain
• contains 5 WD repeats

More general terms

• WD repeat protein family

Additional terms

• SOCS box domain
• WD repeat

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55884
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55884
• UniProt: http://www.uniprot.org/uniprot/Q9NYS7.html