3-phosphoinositide-dependent protein kinase 2 (PDPK2)

Function

• phosphorylates & activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 & RPS6KB1
• may play a general role in signaling processes & in development (putative)
• phosphorylated on Tyr & Ser/Thr

ATP + a protein = ADP + a phosphoprotein

Structure

• belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, PDK1 subfamily
• contains 1 protein kinase domain

Compartment

cytoplasm, peripheral membrane (putative)

Notes

could be the product of a pseudogene

More general terms

• enzyme
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6A1A2.html