synaptobrevin-3; vesicle-associated membrane protein 3; VAMP-3; cellubrevin; CEB (VAMP3, SYB3)
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Function
- trafficking protein from a constitutively recycling pathway (putative)
- may be involved in a membrane fusion complex
- phosphorylated upon DNA damage, probably by ATM or ATR
Structure
- belongs to the synaptobrevin family
- contains 1 v-SNARE coiled-coil homology domain
Compartment
- membrane, cell junction, synapse, synaptosome
Expression
- may be present in all cells
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q15836.html
- ↑ McMahon HT, Ushkaryov YA, Edelmann L, Link E, Binz T, Niemann H, Jahn R, Sudhof TC. Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature. 1993 Jul 22;364(6435):346-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8332193
- ↑ Hurtley SM. Membrane proteins involved in targetted membrane fusion. Trends Biochem Sci. 1993 Dec;18(12):453-5. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8108854