nuclear receptor ROR-beta; retinoid-related orphan receptor-beta; nuclear receptor RZR-beta; nuclear receptor subfamily 1 group F member 2 (RORB, NR1F2, RZRB)

Function

• orphan nuclear receptor
• required for normal postnatal development of rod & cone photoreceptor cells
• regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (putative)

Structure

• belongs to the nuclear hormone receptor family, NR1 subfamily
• contains 1 nuclear receptor DNA-binding domain

Compartment

nucleus (probable)

Alternative splicing

named isoforms=2

More general terms

• nuclear hormone receptor NR1 subfamily
• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/601972
• UniProt: http://www.uniprot.org/uniprot/Q92753.html