sphingosine 1-phosphate receptor 4; S1P receptor 4; S1P4; sphingosine 1-phosphate receptor Edg-6; S1P receptor Edg-6; endothelial differentiation G-protein coupled receptor 6 (S1PR4, EDG6)

Function

• receptor for the lysosphingolipid sphingosine 1-phosphate (S1P)
• may be involved in cell migration processes specific for lymphocytes

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• specifically expressed in fetal & adult lymphoid & hematopoietic tissues,
• expressed in lung, adult & fetal spleen, adult peripheral leukocytes > adult thymus, lymph node, bone marrow, & appendix, fetal liver, thymus, & lung

More general terms

• sphingosine 1-phosphate receptor; S1P receptor (S1PR)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8698
• OMIM: https://mirror.omim.org/entry/603751
• UniProt: http://www.uniprot.org/uniprot/O95977.html