Fos-related antigen 2; FRA-2 (FOSL2 FRA2)

Structure

• heterodimer (putative)
• belongs to the bZIP family, Fos subfamily
• contains 1 bZIP domain
• controls osteoclast survival & size (putative)
• as a dimer with JUN, activates LIF transcription (putative)
• activates CEBPB transcription in PGE2-activated osteoblasts

Compartment

nucleus

More general terms

• fos protein family
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2355
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2355
• OMIM: https://mirror.omim.org/entry/601575
• UniProt: http://www.uniprot.org/uniprot/P15408.html