homeobox protein NANOGP8

Function

• transcription regulator (putative)
• when overexpressed, promotes cells to enter into S phase

Structure

• almost identical to NANOG
• only one change in inferred amino acid sequence from 'Gln-253' in NANOG to His-253 in NANOGP8
• belongs to the Nanog homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Expression

• expressed in breast & urinary bladder tissues

Pathology

• expressed in osteosarcoma, cervical cancer, hepatoma, & breast adenocarcinoma cancer cell lines

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q6NSW7.html