homeobox protein HOX-B6; HOX-2B; HOX-2.2; HU-2 (HOXB6, HOX2B)

Function

• sequence-specific transcription factor
• part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the antp homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• homeobox protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P17509.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3216
• OMIM: https://mirror.omim.org/entry/142961
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3216