homeobox protein HOX-A10; HOX-1H; HOX-1.8; PL (HOXA10, HOX1H)

Function

• sequence-specific transcription factor
• part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
• binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'

Structure

• belongs to the Abd-B homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Alternative splicing

named isoforms=2

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/P31260.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3206
• OMIM: https://mirror.omim.org/entry/142957
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3206