homeobox protein HOX-A5; HOX-1C; HOX 1.3 (HOXA5, HOX1C)

Function

• sequence-specific transcription factor
• part of a developmental regulatory system that provides cells with specific positional identities on the anterior- posterior axis
• also binds to its own promoter
• binds specifically to the motif 5'-CYYNATTA[TG]Y-3'

Structure

• belongs to the antp homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Expression

• expressed during embryogenesis & in adult kidney

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/P20719.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3202
• OMIM: https://mirror.omim.org/entry/142952
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3202