receptor activity-modifying protein 1 (RAMP1, CRLR activity-modifying-protein 1, calcitonin-receptor-like receptor-activity-modifying-protein 1)

Function

• transports calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane
• complex of CALCRL & RAMP1 form receptor for calcitonin- gene-related peptide (CGRP)
• forms heterodimer with CALCRL

Structure

belongs to the RAMP family

Compartment

type 1 membrane protein

Expression

• expressed in uterus, bladder, brain, pancreas, GI tract

More general terms

• receptor activity-modifying protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1026
• OMIM: https://mirror.omim.org/entry/605153
• UniProt: http://www.uniprot.org/uniprot/O60894.html