heat shock protein HSP 90-alpha; HSP 86; renal carcinoma antigen NY-REN-38 (HSP90AA1, HSP90A, HSPC1, HSPCA)

Function

• molecular chaperone
• ATPase activity
• interacts with AHSA1, SMYD3 & TOM34
• interacts with FNIP1 & HSF1

Structure

• homodimer
• belongs to the heat shock protein 90 family

Compartment

• cytoplasm, melanosome
• identified by mass spectrometry in melanosome fractions from stage 1 to stage 4

Alternative splicing

named isoforms=2

More general terms

• heat shock protein [hsp]-90

More specific terms

• heat shock protein HSP 90-alpha A2 (heat shock 90 kD protein 1 alpha-like 3, HSP90AA2, HSPCAL3)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3320
• OMIM: https://mirror.omim.org/entry/140571
• UniProt: http://www.uniprot.org/uniprot/P07900.html