sorting nexin-13; RGS domain- & PHOX domain-containing protein; RGS-PX1 (SNX13, KIAA0713)

Function

• may be involved in several stages of intracellular trafficking
• acts as a GAP for G protein-alpha(s)

Structure

• belongs to the sorting nexin family
• contains 1 PX (phox homology) domain
• contains 1 PXA domain
• contains 1 RGS domain

Alternative splicing

named isoforms=2

Notes

• may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decaye

More general terms

• sorting nexin
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23161
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23161
• OMIM: https://mirror.omim.org/entry/606589
• UniProt: http://www.uniprot.org/uniprot/Q9Y5W8.html