aspartate aminotransferase (AST), glutamine/oxaloacetate transaminase (GOT, SGOT) or transaminase A

Function

• interconverts aspartate & oxalate

Expression

• present in many tissues: heart > liver > skeletal muscle > kidney > brain > pancreas > spleen > lung

Laboratory

• see AST in serum
  • serum AST diminished in pregnancy
• aspartate aminotransferase in body fluid
  • aspartate aminotransferase in amniotic fluid
  • aspartate aminotransferase in dialysis fluid
  • aspartate aminotransferase in gastric fluid
  • aspartate aminotransferase in peritoneal fluid
  • aspartate aminotransferase in pleural fluid
  • aspartate aminotransferase in serum
  • aspartate aminotransferase in synovial fluid
  • aspartate aminotransferase in urine
• aspartate aminotransferase in erythrocytes Compatative biology:
• in eukaryotes there are cytoplasmic, mitochondrial & chloroplastic isozymes

More general terms

• aminotransferase

More specific terms

• cytoplasmic aspartate aminotransferase (GOT1, transaminase A)
• mitochondrial aspartate aminotransferase (glutamate oxaloacetate transaminase 2, mAspAT, fatty acid-binding protein, FABP-1, FABPpm, GOT2, AST2)

Additional terms

• aspartate aminotransferase (AST) in serum (SGOT)