mitochondrial aspartate aminotransferase (glutamate oxaloacetate transaminase 2, mAspAT, fatty acid-binding protein, FABP-1, FABPpm, GOT2, AST2)

Function

• facilitates cellular uptake of long-chain free fatty acids (putative)

L-aspartate + 2-oxoglutarate <--> oxaloacetate + L-glutamate

Cofactor: pyridoxal phosphate

Structure

• homodimer
• belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Compartment

mitochondrial matrix, cell membrane

More general terms

• aspartate aminotransferase
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/P00505.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2806
• OMIM: https://mirror.omim.org/entry/138150