L-aspartate dehydrogenase (ASPDH, ASPD)

Function

• specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (putative)
• iminoaspartate product is unstable in aqueous solution & can decompose to oxaloacetate & ammonia
• cofactor biosynthesis; NAD+ biosynthesis
• iminoaspartate from L-aspartate (dehydrogenase route): step 1

L-aspartate + H2O + NAD+/NADP+ <--> oxaloacetate + NH3 + NADH/NADPH

Structure

belongs to the L-aspartate dehydrogenase family

More general terms

• dehydrogenase

Database

• UniProt: http://www.uniprot.org/uniprot/A6ND91.html