ankyrin repeat & SOCS box protein 11; ASB-11 (ASB11)
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Function
- may be a substrate-recognition component of an elongin-Cullin-SOCS-box protein (ECS) E3 ligase complex which mediates ubiquitination & subsequent proteasomal degradation of target proteins (putative)
- protein modification; protein ubiquitination
Structure
- the SOCS box domain mediates the interaction with the elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes (putative)
- contains 6 ANK repeats
- contains 1 SOCS box domain
Alternative splicing
named isoforms=2