rab40b proto-oncogene protein; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Rar protein (RAB40B SEC4L)

Function

• may be a substrate-recognition component of a SCF-like ECS (elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination & subsequent proteasomal degradation of target proteins (putative)
• protein modification; protein ubiquitination

Structure

• the SOCS box domain mediates the interaction with the elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes (putative)
• belongs to the small GTPase superfamily, Rab family
• contains 1 SOCS box domain

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative)

More general terms

• rab40 proto-oncogene protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q12829.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10966
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10966