elongin (SIII, transcription elongation factor B, TEFB)

Function

• general transcription elongation factor that increases RNA polymerase 2 transcription elongation past template- encoded arresting sites

Structure

• heterotrimer of an A (A1, A2 or A3), B & C subunit regulatory subunits B & C (elongin BC complex)

More general terms

• multisubunit protein
• transcription elongation factor

Additional terms

• elongin BC complex
• positive transcription elongation factor B (P-TEFB, CDK9/cyclin T complex)

Database

• OMIM: https://mirror.omim.org/entry/600786