Na+-independent sulfate anion transporter; solute carrier family 26 member 11 (SLC26A11)

Function

• Na+-independent sulfate anion transporter activity
• may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venule endothelial cells (HEVEC)

Structure

• belongs to the SLC26A/sulP transporter (TC 2.A.53) family
• contains 1 STAS domain

Compartment

• cell membrane
• lysosomal membrane

Expression

• detected in all tissues tested
• highest expression observed in brain, kidney, HEVEC & placenta
• lowest expression in pancreas, skeletal muscle, liver, lung & heart

More general terms

• transmembrane 12e protein
• solute carrier family 26 (SLC26, SLC26A)
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=284129
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:284129
• OMIM: https://mirror.omim.org/entry/610117
• UniProt: http://www.uniprot.org/uniprot/Q86WA9.html