high endothelial venule; high endothelial cell (HEV)
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Introduction
- specialized post-capillary venule (or endothelial cells forming the venule) found in organized secondary lymphoid tissue (tonsils, Peyer patches, mesenteric lymph nodes)
- L-selectin ligands are present in high endothelial venules & play a central role in lymphocyte homing at sites of inflammation